The award winning Tower Museum is located within the city’s historic walls. Permanent exhibitions at the museum include 'The Story of Derry' exhibition and the 'An Armada Shipwreck – La Trinidad Valencera' exhibition. Throughout the year the Museum also plays host to a range of other temporary exhibitions.

Derry city is one of the oldest inhabited settlements in Ireland and has a fascinating history. The Story of Derry exhibition narrates the story from Prehistoric times, the Plantation of Londonderry, the Siege of Derry, through to the growth of Derry during the eighteenth and nineteenth centuries. Life during the twentieth century is also outlined, including the Partition, and the Civil Rights Movement and the impact of the Troubles on the people living here.

'An Armada shipwreck – La Trinidad Valencera' narrates the story of 'La Trinidad Valencera', one of the largest ships in the Armada Fleet. In 1588 it foundered in Kinnagoe Bay in Co. Donegal during a violent storm and was discovered nearly 400 years later by divers from the City of Derry Sub Aqua Club. The exhibition tells the story of the people involved, the soldiers and sailors aboard the Trinidad Valencera and the divers and archaeologists who discovered and excavated the ship. An array of exciting artefacts, on loan from the Ulster Museum, recovered from the ship includes cannons, textiles, pottery, wooden bowls, pewter dishes, goblets, coins and shoes along with many other items.