Ann was born to Thomas Beaumont, a merchant, and his wife Catherine Beaumont in the Parish of St James, Piccadilly, in London, on 17th October 1798. She married William Pierce at St James's on 19th March 1833. After that, they lived at 11 Golden Square, then an address in Harley Street, and then in Belsize Road, where her husband and then she died. There is a gap of ten years from her marriage until portraits appear, which suggests that she was preoccupied with motherhood. Ann and William had two children, Margareta, who married and survived her parents, and John, who died aged 15. Ann died on 12th June 1866. The probate address (a widow living with her daughter and son-in-law) was Elcot House, Belsize Road, London. She exhibited at the Royal Academy between 1820 and 1832, mainly portraits, and lived at various London addresses below and above the east end of Oxford Street: 27 Poland Street (1820), 10 Newman Street (1821–1823) and 44 Upper Charlotte Street (1828–1831).