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This portrait possibly represents Richard Tyson (1730–1784), great-nephew of the famous comparative anatomist Edward Tyson. Richard was educated at Oxford University, and became a fellow of the Royal College of Physicians, London, in 1761. He held many important positions at the RCP, including censor and registrar. He was also physician to St Bartholomew’s Hospital, London.

The doubt over the identity of the sitter is his costume, which is dated to before Richard’s birth. The portrait is therefore probably of another Richard Tyson (1680–1750), son of Edward Tyson, who was also a fellow of the RCP and physician at St Bartholomew’s Hospital, but educated at Cambridge University.